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Research Facilities

Windows Media Video: Medical genomics

Medical genomics:
Connecting genes to health
(Windows Media video, 10 min 24 sec)

In this video, Ray Rodriguez, professor of molecular and cellular biology and a pioneer in genetic engineering, talks about new discoveries scientists are making in regards to food and race. He discusses how our ancestry can determine how likely we are to suffer from some chronic, common diseases — and how future generations can change those risks. [ more… ]

See also: Medical genomics: Connecting genes to health (Quicktime, 10 min 24 sec)

Andy Fell, producer; Ken Zukin, videographer

Media player downloads and troubleshooting

The groundbreaking research that takes place within the College of Biological Sciences at UC Davis offers keys for developing better medical diagnoses and treatments for diseases such a cancer, Alzheimer's, schizophrenia and blindness.

Interdiciplinary research centers unite scientists from across campus in advancing our understanding of life.

Research Facilities


Becton Dickinson Immunocytometry Systems Flow Cytometry Laboratory and Training Facility

This facility houses a FACS Calibur flow cytometry system, used to measure light scatter and fluorescence of single cells or particles. It measures four fluors simultaneously, three from 488 nm excitation and one from 633 nm excitation. The system also has a mechanical sorter. The facility provides flow cytometry training for undergraduates, graduate students, faculty members, and staff members from throughout the campus.
Location: Life Sciences, Room 1110

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Microscopy and Imaging Facility

Microscopy and Imaging Facility, Section of MCB, UC-Davis
An advanced fluorescence microscopy resource specializing in live cell imaging. Welcome to the Imaging Facility run by the Department of Molecular and Cellular Biology. Our facility focuses on the imaging of biological specimens by light microscopy with a special emphasis on the fluorescence imaging of living cells. The facility is located in the Life Sciences building in rooms 1241 and 1242.

Major instruments available in our facility:

  • APLLC DeltaVision-Real Time (RT) Deconvolution Microscope equipped with the Quantitative Laser Module for photokinetics (photokinetic laser lines at 406 and 488 nm).

  • Olympus FV1000 Laser Scanning Confocal equipped with a second, photokinetic scan head (405 nm laser line) and two spectral scan emission detectors.

  • Custom built image-based high throughput screening microscope (screen three colors in three dimensions in a multi-well format).

  • Becton Dickinson FACSCalibur flow cytometer with four channel detection.

Supporting resources:

  • APLLC SoftWorx Explorer Suite PC-based deconvolution software interfaced with BitPlane AG Imaris software for visualization, particle tracking, and co-localization analysis.

  • APLLC Explorer Suite SGI-based deconvolution and visualization software.

  • Huygens Professional image deconvolution software for data containing spherical aberration.

  • Nikon Optiphot-2 Fluorescence Microscope and SimplePCI software for routine screening of samples and acquiring simple two-dimensional digital images.

As of April 1, 2006 the Hitachi SEM will no longer be part of our facility. For questions about access to this instrument, please contact Samantha Barling-Silva, Imaging Facility Manager, Section of Plant Biology (sabarlingsilva@ucdavis.edu; 530-752-9046).


For more information, contact:
Michael Paddy, PhD, Scientific Coordinator, mrpaddy@ucdavis.edu, phone - 530-754-6584
or
Jodi Nunnari, PhD, Chair of MCB Imaging Committee, jmnunnari@ucdavis.edu, phone - 530-754-9774
University of California, Davis
One Shields Avenue
Davis, CA 95616
(530) 752-3611

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W. M. Keck Center for Structural Biology

This center comprises an X-ray crystallography suite, housed in the Chemistry Annex, and a Protein Expression Facility, housed in Briggs Hall. These two facilities collectively support the determination of protein structure using X-ray crystallography.

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X-ray Crystallography Suite

This facility currently houses two rotating anode X-ray generators with two area detectors. One area detector is an image plate named "Raxis-IV." The other area detector is a "Siemens Hi-Star Multiwire."
Location: Chemistry Annex, Room 4445
Contact: Andrew Fisher, associate professor, Department of Chemistry, (530) 754-6180, fisher@chem.ucdavis.edu

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Protein Expression Facility

This facility enables UC Davis scientists and students to use bacteria, yeast, and cell culture systems to produce large quantities of protein necessary for X-ray crystallography studies.
Location: Briggs Hall, Rooms 8 and 16
Contacts: